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Literature summary for 3.4.21.1 extracted from
- An engineered chymotrypsin/cathepsin G site in domain I renders Bacillus thuringiensis Cry3A active against Western corn rootworm larvae (2008), Appl. Environ. Microbiol., 74, 367-374.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli | Diabrotica virgifera |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| alpha-chymostatin | specific inhibitor | Diabrotica virgifera |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Diabrotica virgifera | - |
Diabrotica virgifera virgifera | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| larva | - |
Diabrotica virgifera | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| mCry3A + H2O | Bacillus thuringiensis toxin | Diabrotica virgifera | mCry3A fragments | chymotrypsin cleaves mCry3A into stable 55000 and 49000 Da fragments, as well as smaller polypeptides having molecular masses of 6000 to 11000 Da | ? | |
| additional information | does not cleave the Bacillus thuringiensis toxin Cry3A | Diabrotica virgifera | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| alpha-chymotrypsin | - |
Diabrotica virgifera |
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