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Literature summary for 3.4.21.1 extracted from

  • Cutruzzola, F.; Ascenzi, P.; Barra, D.; Bolognesi, M.; Menegatti, E.; Sarti, P.; Schnebli, H.P.; Tomova, S.; Amiconi, G.
    Selective oxidation of Met-192 in bovine alpha-chymotrypsin. Effect on catalytic and inhibitor binding properties (1993), Biochim. Biophys. Acta, 1161, 201-208.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information selective oxidation of Met192 to its sulfoxide derivative leads to changes of catalytic parameters for the hydrolysis of synthetic substrates and thermodynamic and kinetic interactions with the macromolecular inhibitor eglin c Bos taurus

Inhibitors

Inhibitors Comment Organism Structure
bovine basic panreatic trypsin inhibitor
-
Bos taurus
Eglin c
-
Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Nalpha-benzyloxycarbonyl-L-Ala p-nitrophenyl ester + H2O
-
Bos taurus Nalpha-benzyloxycarbonyl-L-Ala + p-nitrophenol
-
?
Nalpha-benzyloxycarbonyl-L-Leu p-nitrophenyl ester + H2O
-
Bos taurus Nalpha-benzyloxycarbonyl-L-Leu + p-nitrophenol
-
?
Nalpha-benzyloxycarbonyl-L-Lys p-nitrophenyl ester + H2O
-
Bos taurus Nalpha-benzyloxycarbonyl-L-Lys + p-nitrophenol
-
?
Nalpha-benzyloxycarbonyl-L-Tyr p-nitrophenyl ester + H2O
-
Bos taurus Nalpha-benzyloxycarbonyl-L-Tyr + p-nitrophenol
-
?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
additional information
-
additional information
-
Bos taurus