Crystallization (Comment) | Organism |
---|---|
crystal structures of selenium-, sulfur-, and phosphinic acid containing inhibitors bound to porcine pancreatic carboxypeptidase B are determined at 1.7, 2.15 and 1.9 A, respectively | Sus scrofa |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(2S)-7-amino-2-[(hydroxy[(1R)-2-methyl-1-[(3-phenylpropanoyl)amino]propyl]phosphoryl)methyl]heptanoic acid | - |
Sus scrofa | |
3-(6-amino-5-chloropyridin-3-yl)-2-(selanylmethyl)propanoic acid | - |
Sus scrofa | |
7-amino-2-(selanylmethyl)heptanoic acid | - |
Sus scrofa | |
7-amino-2-(sulfanylmethyl)heptanoic acid | - |
Sus scrofa | |
7-amino-2-[(propanoylselanyl)methyl]heptanoic acid | - |
Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | P09955 | - |
- |
Purification (Comment) | Organism |
---|---|
using affinity chromatography and gel filtration | Sus scrofa |
Synonyms | Comment | Organism |
---|---|---|
carboxypeptidase B | - |
Sus scrofa |
ppCPB | - |
Sus scrofa |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000000025 | - |
pH and temperature not specified in the publication | Sus scrofa | 3-(6-amino-5-chloropyridin-3-yl)-2-(selanylmethyl)propanoic acid | |
0.0000011 | - |
pH and temperature not specified in the publication | Sus scrofa | 7-amino-2-[(propanoylselanyl)methyl]heptanoic acid | |
0.000002 | - |
pH and temperature not specified in the publication | Sus scrofa | 7-amino-2-(selanylmethyl)heptanoic acid | |
0.0000055 | - |
pH and temperature not specified in the publication | Sus scrofa | (2S)-7-amino-2-[(hydroxy[(1R)-2-methyl-1-[(3-phenylpropanoyl)amino]propyl]phosphoryl)methyl]heptanoic acid | |
0.000034 | - |
pH and temperature not specified in the publication | Sus scrofa | 7-amino-2-(sulfanylmethyl)heptanoic acid |