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Literature summary for 3.4.17.1 extracted from

  • Kalinina, E.; Biswas, R.; Berezniuk, I.; Hermoso, A.; Aviles, F.X.; Fricker, L.D.
    A novel subfamily of mouse cytosolic carboxypeptidase (2007), FASEB J., 21, 836-850.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
subcloned into pcDNA3 lacking the KpnI site. MYPYDVPDYA ligated into the KpnI site of CCP1, which is located in the C-terminal region following the carboxypeptidase domain. Expression in Neuro2A and NIH3T3 cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information mice lacking Nna1/CCP1 show absence of the detyrosinylated form of alpha-tubulin in mitral cells Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
Homo sapiens 5737
-
cytosol
-
Mus musculus 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
130000
-
Western blot analysis Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
C57B6 mice
-
Mus musculus C57B6
-
C57B6 mice
-

Source Tissue

Source Tissue Comment Organism Textmining
brain broadly distributed Mus musculus
-
cerebellum
-
Mus musculus
-
eye
-
Mus musculus
-
hippocampus
-
Mus musculus
-
olfactory bulb
-
Mus musculus
-
pituitary gland
-
Mus musculus
-
testis abundant Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-tubulin + H2O
-
Mus musculus ?
-
?
alpha-tubulin + H2O
-
Mus musculus C57B6 ?
-
?

Synonyms

Synonyms Comment Organism
Nna1/CCP1
-
Mus musculus
Nna1/CCP1
-
Homo sapiens