Inhibitors | Comment | Organism | Structure |
---|---|---|---|
lactacystin | CatA is inhibited by 0.03 mM lactacystin | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
lysosome | - |
Homo sapiens | 5764 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
32000 | - |
mature form, SDS-PAGE | Homo sapiens |
50000 | - |
proform, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
B-lymphoblastoid cell | - |
Homo sapiens | - |
B-lymphocyte | - |
Homo sapiens | - |
culture condition:antigen-presenting cell | - |
Homo sapiens | - |
myeloid dendritic cell | - |
Homo sapiens | - |
plasmacytoid dendritic cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
FVNQHLCGSHLV + H2O | - |
Homo sapiens | FVNQHLCGSH + L-Leu-L-Val + L-Val | - |
? | |
FVNQHLCGSHLVEAL + H2O | - |
Homo sapiens | FVNQHLCGSHLVE + L-Ala-L-Leu + L-Leu | - |
? | |
additional information | does not cleave the MBPMu4 peptide VVHPFPPIVTPPPP | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CatA | - |
Homo sapiens |
cathepsin A | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | cathepsin A is involved in the C-terminal fine-tuning of antigenic T cell epitopes in human antigen-presenting cells | Homo sapiens |