Inhibitors | Comment | Organism | Structure |
---|---|---|---|
fosinopril | administered as a prodrug and then rapidly converted by the liver and the gastrointestinal mucosa to the active form fosinoprilat | Homo sapiens | |
additional information | angiotensin-converting enzyme inhibition does not significantly modify major biomarkers of inflammation, hemostasis, and endothelial function, e.g. C-reactive protein, interleukin 6, plasminogen activator inhibitor 1, vascular cell adhesion molecule 1, and endothelin 1, while angiotensin II levels are reduced, overview | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
angiotensin I + H2O | Homo sapiens | i.e. DRVYIHPFHL | angiotensin II + His-Leu | i.e. DRVYIHPF | ? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
angiotensin I + H2O | i.e. DRVYIHPFHL | Homo sapiens | angiotensin II + His-Leu | i.e. DRVYIHPF | ? |
Synonyms | Comment | Organism |
---|---|---|
ACE | - |
Homo sapiens |
angiotensin-converting enzyme | - |
Homo sapiens |