Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | pacific hake (Merluccius productus) fillet hydrolysate demonstrates in vitro ACE-inhibitory activity (IC50 0.165 mg/ml), which is enhanced by ultrafiltration through a 10 kDa molecular weight cutoff membrane (IC50 0.044 mg/ml), PeptACE peptides and the unfractionated pacific hake (Merluccius productus) fillet hydrolysate show significantly greater ACE inhibitory activity (i.e., significantly lower IC50 values) after simulated gastrointestinal digestion and may therefore be considered as prodrug type inhibitors | Oryctolagus cuniculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
angiotensin I + H2O | Oryctolagus cuniculus | - |
angiotensin II + L-His-L-Leu | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lung | - |
Oryctolagus cuniculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
angiotensin I + H2O | - |
Oryctolagus cuniculus | angiotensin II + L-His-L-Leu | - |
? | |
hippuryl-L-His-L-Leu + H2O | - |
Oryctolagus cuniculus | hippuric acid + L-His-L-Leu | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ACE | - |
Oryctolagus cuniculus |
angiotensin I-converting enzyme | - |
Oryctolagus cuniculus |