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Literature summary for 3.4.15.1 extracted from

  • Shen, X.Z.; Xiao, H.D.; Li, P.; Lin, C.X.; Fuchs, S.; Bernstein, K.E.
    Tissue specific expression of angiotensin converting enzyme: a new way to study an old friend (2008), Int. Immunopharmacol., 8, 171-176.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Mus musculus
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creation of mice with angiotensin converting enzyme expression limited to selected tissue types
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Source Tissue

Source Tissue Comment Organism Textmining
heart mice with angiotensin converting enzyme expression only in the heart show atria enlargement and electrical conduction defects but normal ventricular function Mus musculus
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macrophage mice with expression of angiotensin convertzing enzyme only in monocytes and macrophages have a marked resistance to the growth of melanoma due to an enhanced immune response Mus musculus
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monocyte mice with expression of angiotensin convertzing enzyme only in monocytes and macrophages have a marked resistance to the growth of melanoma due to an enhanced immune response Mus musculus
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