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Literature summary for 3.4.15.1 extracted from

  • Farias, S.L.; Sabatini, R.A.; Sampaio, T.C.; Hirata, I.Y.; Cezari, M.H.; Juliano, M.A.; Sturrock, E.D.; Carmona, A.K.; Juliano, L.
    Angiotensin I-converting enzyme inhibitor peptides derived from the endostatin-containing NC1 fragment of human collagen XVIII (2006), Biol. Chem., 387, 611-616.
    View publication on PubMed
Search for more literature for 3.4.15.1

Inhibitors

Inhibitors Comment Organism Structure
(pE)KWAP
-
 Homo sapiens
(pE)WPRPQIPP
-
 Homo sapiens
LRPARPTSPP
-
 Homo sapiens
LRPARPTSPPA
-
 Homo sapiens
additional information synthetic peptides derived from human collagen XVIII hinge domain with sequences similar to bradykinin potentiating peptides from snake venom Homo sapiens
PARPTSPP
-
 Homo sapiens
RPARPTSPP
-
 Homo sapiens
Ser-Pro-Pro
-
 Homo sapiens
SSYVHLRPARPTSPP
-
 Homo sapiens
YVHLRPARPTSPP
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 recombinant
-

Source Tissue

Source Tissue Comment Organism Textmining
testis
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Abz-YRK(2,4-dinitrophenyl)P + H2O
-
 Homo sapiens ?
-
 ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.000003
-
 (pE)WPRPQIPP 37°C, pH 7.0, full-length mutant containing only a functional C-domain catalytic site Homo sapiens
0.00001
-
 (pE)WPRPQIPP 37°C, pH 7.0, enzyme from testis Homo sapiens
0.00003
-
 (pE)WPRPQIPP 37°C, pH 7.0, recombinant wild-type enzyme Homo sapiens
0.0001
-
 (pE)WPRPQIPP 37°C, pH 7.0, full-length mutant containing only a functional N-domain catalytic site Homo sapiens
0.0003
-
 LRPARPTSPPA 37°C, pH 7.0, enzyme from testis Homo sapiens
0.0004
-
 (pE)KWAP 37°C, pH 7.0, recombinant wild-type enzyme Homo sapiens
0.0006
-
 (pE)KWAP 37°C, pH 7.0, full-length mutant containing only a functional N-domain catalytic site Homo sapiens
0.0007
-
 (pE)KWAP 37°C, pH 7.0, full-length mutant containing only a functional C-domain catalytic site Homo sapiens
0.0008
-
 LRPARPTSPP 37°C, pH 7.0, enzyme from testis Homo sapiens
0.0008
-
 YVHLRPARPTSPP 37°C, pH 7.0, enzyme from testis Homo sapiens
0.0008
-
 (pE)KWAP 37°C, pH 7.0, enzyme from testis Homo sapiens
0.0009
-
 RPARPTSPP 37°C, pH 7.0, full-length mutant containing only a functional C-domain catalytic site Homo sapiens
0.001
-
 RPARPTSPP 37°C, pH 7.0, enzyme from testis Homo sapiens
0.0015
-
 PARPTSPP 37°C, pH 7.0, enzyme from testis Homo sapiens
0.002
-
 YVHLRPARPTSPP 37°C, pH 7.0, full-length mutant containing only a functional C-domain catalytic site Homo sapiens
0.0021
-
 PARPTSPP 37°C, pH 7.0, full-length mutant containing only a functional C-domain catalytic site Homo sapiens
0.0024
-
 SSYVHLRPARPTSPP 37°C, pH 7.0, enzyme from testis Homo sapiens
0.0026
-
 LRPARPTSPP 37°C, pH 7.0, recombinant wild-type enzyme Homo sapiens
0.0031
-
 SSYVHLRPARPTSPP 37°C, pH 7.0, full-length mutant containing only a functional C-domain catalytic site Homo sapiens
0.0032
-
 LRPARPTSPP 37°C, pH 7.0, full-length mutant containing only a functional C-domain catalytic site Homo sapiens
0.0046
-
 LRPARPTSPPA 37°C, pH 7.0, full-length mutant containing only a functional C-domain catalytic site Homo sapiens
0.005
-
 Ser-Pro-Pro 37°C, pH 7.0, enzyme from testis Homo sapiens
0.0053
-
 PARPTSPP 37°C, pH 7.0, recombinant wild-type enzyme Homo sapiens
0.0058
-
 YVHLRPARPTSPP 37°C, pH 7.0, recombinant wild-type enzyme Homo sapiens
0.0068
-
 RPARPTSPP 37°C, pH 7.0, recombinant wild-type enzyme Homo sapiens
0.0069
-
 Ser-Pro-Pro 37°C, pH 7.0, recombinant wild-type enzyme Homo sapiens
0.0077
-
 SSYVHLRPARPTSPP 37°C, pH 7.0, recombinant wild-type enzyme Homo sapiens
0.01
-
 YVHLRPARPTSPP 37°C, pH 7.0, full-length mutant containing only a functional N-domain catalytic site Homo sapiens
0.012
-
 LRPARPTSPPA 37°C, pH 7.0, full-length mutant containing only a functional N-domain catalytic site Homo sapiens
0.013
-
 Ser-Pro-Pro 37°C, pH 7.0, full-length mutant containing only a functional N-domain catalytic site Homo sapiens
0.017
-
 LRPARPTSPP 37°C, pH 7.0, full-length mutant containing only a functional N-domain catalytic site Homo sapiens
0.017
-
 LRPARPTSPPA 37°C, pH 7.0, recombinant wild-type enzyme Homo sapiens
0.019
-
 Ser-Pro-Pro 37°C, pH 7.0, full-length mutant containing only a functional C-domain catalytic site Homo sapiens
0.023
-
 RPARPTSPP 37°C, pH 7.0, full-length mutant containing only a functional N-domain catalytic site Homo sapiens
0.049
-
 PARPTSPP 37°C, pH 7.0, full-length mutant containing only a functional N-domain catalytic site Homo sapiens
0.2
-
 SSYVHLRPARPTSPP 37°C, pH 7.0, full-length mutant containing only a functional N-domain catalytic site Homo sapiens