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Literature summary for 3.4.15.1 extracted from

  • Andujar-Sanchez, M.; Camara-Artigas, A.; Jara-Perez, V.
    Purification of angiotensin I converting enzyme from pig lung using concanavalin-A Sepharose chromatography (2003), J. Chromatogr. B, 783, 247-252.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.23
-
2-furylacryloyl-Phe-Gly-Gly pH 7.5, 25°C Sus scrofa
0.25
-
2-furylacryloyl-Phe-Gly-Gly pH 7.5, 25°C, cobalt-ACE Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
angiotensin I + H2O Sus scrofa enzyme plays a major role in blood pressure regulation angiotensin II + His-Leu
-
?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
ACE and cobalt-ACE Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
lung
-
Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-furylacryloyl-Phe-Gly-Gly + H2O
-
Sus scrofa 2-furylacrylic acid + Phe-Gly-Gly
-
?
angiotensin I + H2O
-
Sus scrofa angiotensin II + His-Leu
-
?
angiotensin I + H2O enzyme plays a major role in blood pressure regulation Sus scrofa angiotensin II + His-Leu
-
?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
5520
-
2-furylacryloyl-Phe-Gly-Gly pH 7.5, 25°C, cobalt-ACE Sus scrofa
7590
-
2-furylacryloyl-Phe-Gly-Gly pH 7.5, 25°C Sus scrofa