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Literature summary for 3.4.14.5 extracted from

  • Lim, K.S.; Cho, J.Y.; Kim, B.H.; Kim, J.R.; Kim, H.S.; Kim, D.K.; Kim, S.H.; Yim, H.J.; Lee, S.H.; Shin, S.G.; Jang, I.J.; Yu, K.S.
    Pharmacokinetics and pharmacodynamics of LC15-0444, a novel dipeptidyl peptidase IV inhibitor, after multiple dosing in healthy volunteers (2009), Br. J. Clin. Pharmacol., 68, 883-890.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.14.5

Inhibitors

Inhibitors Comment Organism Structure
LC15-0444 selective and competitive inhibitor of dipeptidyl peptidase IV, more than 80% inhibition of DPP IV activity from baseline is sustained for more than 24 h in all dose groups (200, 400 or 600 mg of LC15-0444 once daily for 10 days) Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gly-L-Pro-4-nitroanilide + H2O
-
 Homo sapiens Gly-L-Pro + 4-nitroaniline
-
 ?

Synonyms

Synonyms Comment Organism
CD26
-
 Homo sapiens
dipeptidyl peptidase IV
-
 Homo sapiens
DPPIV
-
 Homo sapiens