Application | Comment | Organism |
---|---|---|
medicine | DPP-4 inhibition in combination with metformin is an efficient, safe and tolerable combination therapy for type 2 diabetes | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
NVP-DPP728 | - |
Homo sapiens | |
saxagliptin | - |
Homo sapiens | |
sitagliptin | MK-0431, trade name Januvia, 100 mg sitagliptin inhibits plasma DPP-4 activity for more than 16 hours after a single administration | Homo sapiens | |
vildagliptin | LAF237, trade name Galvus, 100 mg vildagliptin inhibits plasma DPP-4 activity for more than 16 hours after a single administration | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
glucagon-like peptide 1 + H2O | Homo sapiens | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glucagon-like peptide 1 + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
dipeptidyl peptidase-4 | - |
Homo sapiens |
DPP-4 | - |
Homo sapiens |