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Literature summary for 3.4.14.5 extracted from

  • Dubois, V.; Lambeir, A.M.; Van der Veken, P.; Augustyns, K.; Creemers, J.; Chen, X.; Scharpe, S.; De Meester, I.
    Purification and characterization of dipeptidyl peptidase IV-like enzymes from bovine testes (2008), Front. Biosci., 13, 3558-3568.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
AB192 i.e. bis(4-acetamidophenyl) 1-((S)-prolyl)pyrrolidine-2(R,S)-phosphonate hydrochloride Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
glucagon-like peptide 1 + H2O Bos taurus
-
?
-
?
glucose-dependent insulinotropic polypeptide + H2O Bos taurus
-
?
-
?
neuropeptide Y + H2O Bos taurus
-
?
-
?
peptide YY + H2O Bos taurus
-
?
-
?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
DEAE Sepharose column chromatography Con A-Sepharose column chromatography, HiTrap nickel-chelating column chromatography, HiTrap phenyl column chromatography, ammonium sulfate precipitation, HiTrap Q column chromatography, Superdex 200 gel filtration, and Lys-isoindole affinity gel filtration Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
testis
-
Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glucagon-like peptide 1 + H2O
-
Bos taurus ?
-
?
glucose-dependent insulinotropic polypeptide + H2O
-
Bos taurus ?
-
?
Gly-L-Pro-4-nitroanilide
-
Bos taurus Gly-L-Pro + 4-nitroaniline
-
?
L-Ala-L-Pro-4-nitroanilide
-
Bos taurus L-Ala-L-Pro + 4-nitroaniline
-
?
L-Arg-L-Pro-4-nitroanilide
-
Bos taurus L-Arg-L-Pro + 4-nitroaniline
-
?
neuropeptide Y + H2O
-
Bos taurus ?
-
?
peptide YY + H2O
-
Bos taurus ?
-
?

Synonyms

Synonyms Comment Organism
dipeptidyl peptidase-4
-
Bos taurus
DPPIV
-
Bos taurus