Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.14.5 extracted from

  • Deacon, C.F.
    Alogliptin, a potent and selective dipeptidyl peptidase-IV inhibitor for the treatment of type 2 diabetes (2008), Curr. Opin. Investig. Drugs, 9, 402-413.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
alogliptin synonyms are alogliptin benzoate, SYR-085, SYR-322, SYR-619, SYR-11792, SYR-110085A, SYR-111791, or TAK-322, highly potent and selective dipeptidyl peptidase-IV inhibitor for the treatment of type 2 diabetes, non-covalent inhibitor of DPP-IV with selectivity of more than 10000fold over other proteases including tryptase, DPP-2, DPP-8, DPP-9, fibroblast activation protein/seprase and prolyl endopeptidase Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
dipeptidyl peptidase-IV
-
Homo sapiens
DPP-IV
-
Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.000007
-
-
Homo sapiens alogliptin