Inhibitors | Comment | Organism | Structure |
---|---|---|---|
saxagliptin | highly potent and selective inhibitor of DPP-IV | Homo sapiens | |
sitagliptin | selective inhibitor of DPP-IV, over 80% inhibition of DPP-IV with a single oral dose of 50 mg | Homo sapiens | |
vildagliptin | highly potent and stable selective inhibitor of DPP-IV, over 90% inhibition of DPP-IV with a single oral dose of 100 mg | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
breast | - |
Homo sapiens | - |
endothelial cell | - |
Homo sapiens | - |
intestine | - |
Homo sapiens | - |
kidney | most densely located in the kidney | Homo sapiens | - |
liver | - |
Homo sapiens | - |
lymphocyte | - |
Homo sapiens | - |
macrophage | - |
Homo sapiens | - |
ovary | - |
Homo sapiens | - |
placenta | - |
Homo sapiens | - |
thyroid gland | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glucagon-like peptide 1 + H2O | - |
Homo sapiens | ? | - |
? | |
glucose-dependent insulinotropic peptide + H2O | - |
Homo sapiens | ? | - |
? | |
growth hormone-releasing hormone + H2O | - |
Homo sapiens | ? | - |
? | |
neuropeptide Y + H2O | - |
Homo sapiens | ? | - |
? | |
peptide YY + H2O | - |
Homo sapiens | ? | - |
? | |
pituitary adenylate cyclase activating peptide + H2O | - |
Homo sapiens | ? | - |
? | |
Substance P + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
dipeptidyl peptidase-IV | - |
Homo sapiens |
DPP-IV | - |
Homo sapiens |