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Literature summary for 3.4.14.5 extracted from
- CD26 inhibition on CD34+ or lineage- human umbilical cord blood donor hematopoietic stem cells/hematopoietic progenitor cells improves long-term engraftment into NOD/SCID/Beta2null immunodeficient mice (2007), Stem Cells Dev., 16, 355-360.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | CD26 on donor human cord blood cells is a negative regulator of the engraftment of long-term repopulating cells. CD26 inhibitor treatment of donor cells prior to transplant has the ability to improve long-term engraftment | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Diprotin A | - |
Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| hematopoietic stem cell | from umbilical cord blood | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Gly-Pro 4-nitroanilide + H2O | - |
Homo sapiens | Gly-Pro + 4-nitroaniline | - |
? | |
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