Application | Comment | Organism |
---|---|---|
medicine | the oral dipeptidyl peptidase 4 inhibitors vildagliptin, sitagliptin, and saxagliptin are efficious both alone and in association with other oral anti-diabetic agents and may be administered in a single daily dose. They have substantial advantages with respect to other anti-diabetic drugs, since they involve a low risk of hypoglycemia and do not affect body weight | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
saxagliptin | the oral dipeptidyl peptidase 4 inhibitor is efficious both alone and in association with other oral anti-diabetic agents and may be administered in a single daily dose, the inhibitor has low risk of hypoglycemia and does not affect body weight | Homo sapiens | |
sitagliptin | the oral dipeptidyl peptidase 4 inhibitor is efficious both alone and in association with other oral anti-diabetic agents and may be administered in a single daily dose, the inhibitor has low risk of hypoglycemia and does not affect body weight | Homo sapiens | |
vildagliptin | the oral dipeptidyl peptidase 4 inhibitor is efficious both alone and in association with other oral anti-diabetic agents and may be administered in a single daily dose, the inhibitor has low risk of hypoglycemia and does not affect body weight | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glucagon-like peptide-1 + H2O | - |
Homo sapiens | ? | - |
? | |
glucose-dependent insulinotropic polypeptide + H2O | - |
Homo sapiens | ? | - |
? |