Application | Comment | Organism |
---|---|---|
medicine | CD26 inhibition may represent a novel approach to increasing the efficacy and success of hematopoietic stem cell/hematopoietic progenitor cell transplantation, especially under conditions of limiting donor cell yield | Mus musculus |
medicine | CD26 inhibition may represent a novel approach to increasing the efficacy and success of hematopoietic stem cell/hematopoietic progenitor cell transplantation, especially under conditions of limiting donor cell yield | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Diprotin A | - |
Homo sapiens | |
Diprotin A | - |
Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cell surface | - |
Mus musculus | 9986 | - |
cell surface | - |
Homo sapiens | 9986 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
SDF-1/CXCL12 + H2O | Mus musculus | CD26 may play a role in SDF-1/CXCL12 mediated functions such as chemotaxis | ? | - |
? | |
SDF-1/CXCL12 + H2O | Homo sapiens | CD26 may play a role in SDF-1/CXCL12 mediated functions such as chemotaxis | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
bone marrow | - |
Mus musculus | - |
hematopoietic stem cell | - |
Mus musculus | - |
hematopoietic stem cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
SDF-1/CXCL12 + H2O | CD26 may play a role in SDF-1/CXCL12 mediated functions such as chemotaxis | Mus musculus | ? | - |
? | |
SDF-1/CXCL12 + H2O | CD26 may play a role in SDF-1/CXCL12 mediated functions such as chemotaxis | Homo sapiens | ? | - |
? | |
SDF-1/CXCL12 + H2O | CD26 can cleave SDF-1/CXCL12 to a chemotactically-null molecule | Mus musculus | ? | - |
? | |
SDF-1/CXCL12 + H2O | CD26 can cleave SDF-1/CXCL12 to a chemotactically-null molecule | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
dipeptidylpeptidase IV/CD26 | - |
Mus musculus |
dipeptidylpeptidase IV/CD26 | - |
Homo sapiens |