Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Syrrx106124 | acutely lowers blood glucose and enhances glucose-stimulated insulin secretion in wild-type mice and in mice with targeted disruption of single incretin receptors | Mus musculus | |
TP8211 | acutely lowers blood glucose and enhances glucose-stimulated insulin secretion in wild-type mice and in mice with targeted disruption of single incretin receptors | Mus musculus | |
valine pyrrolidide | - |
Sus scrofa | |
vildagliptin | acutely lowers blood glucose and enhances glucose-stimulated insulin secretion in wild-type mice and in mice with targeted disruption of single incretin receptors | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | DPP-4 is an important determinant of incretin inactivation | ? | - |
? | |
additional information | Mus musculus | DPP-4 plays a role in the control of immune function, inflammatory responses, and behavior | ? | - |
? | |
additional information | Rattus norvegicus | DPP-4 plays a role in the control of immune function, inflammatory responses, and behavior | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Sus scrofa | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
nose | levels of tissue DPP-4 are reduced in nasal tissue of human subjects with chronic rhinosinusitis | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glucagon-like peptide-1 + H2O | - |
Homo sapiens | ? | - |
? | |
glucagon-like peptide-1 + H2O | - |
Sus scrofa | ? | - |
? | |
glucose-dependent insulinotropic polypeptide + H2O | - |
Homo sapiens | ? | - |
? | |
glucose-dependent insulinotropic polypeptide + H2O | - |
Sus scrofa | ? | - |
? | |
additional information | DPP-4 is an important determinant of incretin inactivation | Homo sapiens | ? | - |
? | |
additional information | DPP-4 plays a role in the control of immune function, inflammatory responses, and behavior | Mus musculus | ? | - |
? | |
additional information | DPP-4 plays a role in the control of immune function, inflammatory responses, and behavior | Rattus norvegicus | ? | - |
? | |
Substance P + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DPP-4 | - |
Mus musculus |
DPP-4 | - |
Homo sapiens |
DPP-4 | - |
Rattus norvegicus |
DPP-4 | - |
Sus scrofa |