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Literature summary for 3.4.14.5 extracted from

  • Jackson, E.K.; Dubinion, J.H.; Mi, Z.
    Effects of dipeptidyl peptidase iv inhibition on arterial blood pressure (2008), Clin. Exp. Pharmacol. Physiol., 35, 29-34.
    View publication on PubMed

Application

Application Comment Organism
medicine in genetically susceptible animals, inhibition of DPP IV increases arterial blood pressure via Y1 receptors when elevated blood pressure is reduced with antihypertensive drugs provided that the sympathetic nervous system is functional Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
3-N-[(2S,3S)-2-amino-3-methylpentanoyl]-1,3-thiazolidine in genetically susceptible animals, inhibition of DPP IV increases arterial blood pressure via Y1 receptors when elevated blood pressure is reduced with antihypertensive drugs provided that the sympathetic nervous system is functional Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Synonyms

Synonyms Comment Organism
CD26
-
Rattus norvegicus
dipeptidyl peptidase IV
-
Rattus norvegicus
DPP IV
-
Rattus norvegicus