Inhibitors | Comment | Organism | Structure |
---|---|---|---|
L-isoleucinepyrrolidine | IC50: 0.022 mM | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.159 | - |
Gly-Pro-glycinamide | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Gly-Pro-glycinamide + H2O | Homo sapiens | CD26 plays a direct regulatory and indispensable role in the eventual antiretroviral activity of small synthetic molecules such as the antiretroviral prodrug Gly-Pro-glycinamide | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
T-lymphocyte cell line | CEM, C8166, Molt4/C8, MT-4 | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Gly-Phe-4-nitroanilide + H2O | - |
Homo sapiens | Gly-Phe + 4-nitroaniline | - |
? | |
Gly-Pro-glycinamide + H2O | CD26 plays a direct regulatory and indispensable role in the eventual antiretroviral activity of small synthetic molecules such as the antiretroviral prodrug Gly-Pro-glycinamide | Homo sapiens | ? | - |
? | |
Gly-Pro-glycinamide + H2O | the anti-HIV drug Gly-Pro-glycinamide is not active as such, but rather behaves as a prodrug that must be obligatorily cleaved by VD26/DPP IV to Gly-Pro and glycinamide to exert its antiretroviral activity | Homo sapiens | Gly-Pro + glycinamide | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CD26 | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.022 | - |
IC50: 0.022 mM | Homo sapiens | L-isoleucinepyrrolidine |