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Literature summary for 3.4.14.5 extracted from

  • Pala, L.; Mannucci, E.; Pezzatini, A.; Ciani, S.; Sardi, J.; Raimondi, L.; Ognibene, A.; Cappadona, A.; Vannelli, B.G.; Rotella, C.M.
    Dipeptidyl peptidase-IV expression and activity in human glomerular endothelial cells (2003), Biochem. Biophys. Res. Commun., 310, 28-31.
    View publication on PubMed
Search for more literature for 3.4.14.5

Activating Compound

Activating Compound Comment Organism Structure
glucose increases enzyme expression in glucose-treated glomerular endothelial cells, glucose effect on the enzyme is probably responsible for the reduction of glucagon-like peptide-1 in type II diabetic patients Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
glucagon-like peptide 1 + H2O Homo sapiens i.e. GLP-1, degradation, regulation of activity ?
-
 ir

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
endothelium glomerular endothelial cells Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glucagon-like peptide 1 + H2O i.e. GLP-1, degradation, regulation of activity Homo sapiens ?
-
 ir
glucagon-like peptide-1 + H2O i.e. GLP-1, degradation Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
DPP-IV
-
 Homo sapiens