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Literature summary for 3.4.14.5 extracted from

  • Kaehne, T.; Reinhold, D.; Neubert, K.; Born, I.; Faust, J.; Ansorge, S.
    Signal transduction events induced or affected by inhibition of the catalytic activity of dipeptidyl peptidase IV (DP IV, CD26) (2000), Adv. Exp. Med. Biol., 477, 131-137.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
Lys[benzyloxycarbonyl(NO2)]-thiazolidide
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane cell surface Homo sapiens 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens enzyme plays an important role in the process of activation and proliferation of lymphocytes, inhibition of the enzyme activity results in induction or mediation of diverse cellular processes and effects, such as induction of tyrosine phosphorylations, p38 MAP kinase activation, induction of TGF-beta1 secretion, suppression of DNA synthesis and proliferation, reduced production of various cytokines, and alteration anti-CD3-induced signalling pathways, overview ?
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
T-cell
-
 Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme plays an important role in the process of activation and proliferation of lymphocytes, inhibition of the enzyme activity results in induction or mediation of diverse cellular processes and effects, such as induction of tyrosine phosphorylations, p38 MAP kinase activation, induction of TGF-beta1 secretion, suppression of DNA synthesis and proliferation, reduced production of various cytokines, and alteration anti-CD3-induced signalling pathways, overview Homo sapiens ?
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 ?