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Literature summary for 3.4.14.5 extracted from

  • Miura, S.; Song, I.S.; Morita, A.; Erickson, R.H.; Kim, Y.S.
    Distribution and biosynthesis of aminopeptidase N and dipeptidyl aminopeptidase IV in rat small intestine (1983), Biochim. Biophys. Acta, 761, 66-75.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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Posttranslational Modification

Posttranslational Modification Comment Organism
additional information two-fold activation of precursor enzyme form occurs during transfer from the Golgi membranes to the brush border membranes Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
small intestine maximally expressed in mid-villus cells, substantial activity in the crypt cells, primarily associated with brush border membranes in all segments, in the proximal intestine, a significant amount of the enzyme is associated with the cytosol fraction. Cytosol and brush border membrane forms are immunologically identical Rattus norvegicus
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