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Literature summary for 3.4.13.19 extracted from

  • Kropp, H.; Sundelof, J.G.; Hajdu, R.; Kahan, F.M.
    Metabolism of thienamycin and related carbapenem antibiotics by the renal dipeptidase, dehydropeptidase (1982), Antimicrob. Agents Chemother., 22, 62-70.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
EDTA
-
Canis lupus familiaris
EDTA
-
Pan troglodytes

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Canis lupus familiaris 16020
-
membrane
-
Pan troglodytes 16020
-

Organism

Organism UniProt Comment Textmining
Canis lupus familiaris
-
-
-
Pan troglodytes
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
Canis lupus familiaris
-
kidney
-
Pan troglodytes
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-acylated carbapenems + H2O
-
Canis lupus familiaris ?
-
?
N-acylated carbapenems + H2O
-
Pan troglodytes ?
-
?
N-formimidoyl thienamycin derivative MK0787 + H2O hydrolysis of the beta-lactam ring Canis lupus familiaris ?
-
?
N-formimidoyl thienamycin derivative MK0787 + H2O hydrolysis of the beta-lactam ring Pan troglodytes ?
-
?
nonbasic N-acylated thienamycin + H2O
-
Canis lupus familiaris ?
-
?
nonbasic N-acylated thienamycin + H2O
-
Pan troglodytes ?
-
?
thienamycin + H2O hydrolysis of the beta-lactam ring Canis lupus familiaris ?
-
?
thienamycin + H2O hydrolysis of the beta-lactam ring Pan troglodytes ?
-
?