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Literature summary for 3.3.2.6 extracted from

  • Westergren, V.S.; Wilson, S.J.; Penrose, J.F.; Howarth, P.H.; Sampson, A.P.
    Nasal mucosal expression of the leukotriene and prostanoid pathways in seasonal and perennial allergic rhinitis (2009), Clin. Exp. Allergy, 39, 820-828.
    View publication on PubMed
Search for more literature for 3.3.2.6

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
leukotriene A4 + H2O Homo sapiens
-
 leukotriene B4
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
basophil
-
 Homo sapiens
-
eosinophil
-
 Homo sapiens
-
epithelium of the nasal airway Homo sapiens
-
lamina propria
-
 Homo sapiens
-
mast cell
-
 Homo sapiens
-
monocyte
-
 Homo sapiens
-
additional information immunohistochemical analysis, overview Homo sapiens
-
nasal cavity enzyme expression analysis, overview Homo sapiens
-
neutrophil
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
leukotriene A4 + H2O
-
 Homo sapiens leukotriene B4
-
 ?

Synonyms

Synonyms Comment Organism
LT A4 hydrolase
-
 Homo sapiens
LTA4 hydrolase
-
 Homo sapiens

General Information

General Information Comment Organism
metabolism no difference in LTA4 hydrolase expression in patients with naturally occurring allergic rhinitis compared to controls, suggesting that LTB4 is less important chronically or that LTA4 hydrolase is not the rate-limiting step in its synthesis Homo sapiens