Inhibitors | Comment | Organism | Structure |
---|---|---|---|
[6]-gingerol | from ginger, [6]-gingerol suppresses anchorage-independent cancer cell growth by inhibiting LTA4H activity in HCT116 colorectal cancer cells, overview. [6]-Gingerol specifically binds with LTA4H in vitro and ex vivo | Homo sapiens | |
[6]-gingerol | from ginger, [6]-gingerol suppresses anchorage-independent cancer cell growth by inhibiting LTA4H activity in mice, overview. [6]-Gingerol specifically binds with LTA4H in vitro and ex vivo | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P09960 | - |
- |
Mus musculus | - |
NIH Swiss nude mice | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
colorectal cancer cell | - |
Mus musculus | - |
colorectal cancer cell | - |
Homo sapiens | - |
HCT-116 cell | high expression level | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
leukotriene A4 hydrolase | - |
Mus musculus |
leukotriene A4 hydrolase | - |
Homo sapiens |
LTA4H | - |
Mus musculus |
LTA4H | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | knockdown of LTA4H inhibits anchorage-independent growth of HCT116 colon cancer cells | down |