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Literature summary for 3.3.2.6 extracted from

  • Jame, A.J.; Lackie, P.M.; Cazaly, A.M.; Sayers, I.; Penrose, J.F.; Holgate, S.T.; Sampson, A.P.
    Human bronchial epithelial cells express an active and inducible biosynthetic pathway for leukotrienes B4 and C4 (2007), Clin. Exp. Allergy, 37, 880-892.
    View publication on PubMed
Search for more literature for 3.3.2.6

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
68000
-
 determinend by SDS-PAGE and Western Blot analysis Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate + H2O Homo sapiens
-
 (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
16HBE14o cell
-
 Homo sapiens
-
bronchial epithelial cell HBEC Homo sapiens
-
eosinophil used as control for the expression of 5-LO pathway enzymes Homo sapiens
-
HeLa cell used as control for the expression of 5-LO pathway enzymes Homo sapiens
-
KU-812F cell used as control for the expression of 5-LO pathway enzymes Homo sapiens
-
leukocyte used as control for the expression of 5-LO pathway enzymes Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate + H2O
-
 Homo sapiens (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate
-
 ?

Synonyms

Synonyms Comment Organism
leukotriene-A4 hydrolase
-
 Homo sapiens