Application | Comment | Organism |
---|---|---|
medicine | the enzyme catalyses the hydrolysis of leukotriene A4 into the proinflammatory substance leukotriene B4 | Cavia porcellus |
medicine | the enzyme catalyses the hydrolysis of leukotriene A4 into the proinflammatory substance leukotriene B4 | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
leukotriene A4 + H2O | Homo sapiens | biosynthesis of leukotriene B4 | leukotriene B4 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cavia porcellus | - |
- |
- |
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
additional information | enzyme is susceptible to proteolytic digestion | Cavia porcellus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Cavia porcellus | - |
kidney | - |
Homo sapiens | - |
liver | - |
Cavia porcellus | - |
liver | - |
Homo sapiens | - |
lung | - |
Cavia porcellus | - |
lung | - |
Homo sapiens | - |
Storage Stability | Organism |
---|---|
-20°C, 95% of activity after 12 days | Cavia porcellus |
4°C, 50% loss of activity after 12 days | Cavia porcellus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
leukotriene A4 + H2O | - |
Cavia porcellus | leukotriene B4 | - |
? | |
leukotriene A4 + H2O | - |
Homo sapiens | leukotriene B4 | - |
? | |
leukotriene A4 + H2O | biosynthesis of leukotriene B4 | Homo sapiens | leukotriene B4 | - |
? |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
56 | - |
1 h, complete loss of activity | Cavia porcellus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | 8.5 | - |
Cavia porcellus |