Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21(DE3) cells | Escherichia coli |
Protein Variants | Comment | Organism |
---|---|---|
F111A | the mutant displays a significant increase in the average diffusion constant compared to the wild-type protein with no enzymatic activity on DNA containing 8-oxoguanine residues opposite cytosine. The mutant has little or no ability to form a Schiff base with 8-oxoguanine residues opposite cytosine or 5,6-dihydrouracil opposite guanine compared to wild type enzyme | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA containing 8-oxoguanine residues + H2O | 8-oxoguanine residues opposite cytosine | Escherichia coli | 8-oxoguanine + DNA | - |
? | |
additional information | formamidopyrimidine DNA glycosylase is specific for oxidized purines | Escherichia coli | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
formamidopyrimidine DNA glycosylase | - |
Escherichia coli |
FPG | - |
Escherichia coli |