Literature summary for 3.2.2.23 extracted from

Morawiec, Z.; Janik, K.; Kowalski, M.; Stetkiewicz, T.; Szaflik, J.; Morawiec-Bajda, A.; Sobczuk, A.; Blasiak, J.
DNA damage and repair in children with Downs syndrome (2008), Mutat. Res., 637, 118-123.

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Application

Application	Comment	Organism
medicine	cells from children with Down's syndrome do not display an effective DNA repair after treatment with 10 mM hydrogen peroxide. No difference in the sensitivity to DNA-damaging agents and the efficacy of DNA repair due to age and gender in children with Down's syndrome is observed	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	children with Down's syndrome	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
lymphocyte	-	Homo sapiens	-

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Release 2023.1 (January 2023)