Literature summary for 3.2.2.23 extracted from

Rogacheva, M.; Ishchenko, A.; Saparbaev, M.; Kuznetsova, S.; Ogryzko, V.
High resolution characterization of formamidopyrimidine-DNA glycosylase interaction with its substrate by chemical cross-linking and mass spectrometry using substrate analogs (2006), J. Biol. Chem., 281, 32353-32365.

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Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	isoform Fpg	-
Homo sapiens	-	isoform Ogg1	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	cross-linking of active center with a series of reactive oligonucleotide duplexes containing both a single 8-oxoguanine residue and an O-ethyl-substituted diphosphate internucleotide group results in identification of eight phosphate groups on both strands of the DNA duplex specifically interacting with nucleophilic amino acids of the enzyme. L249 of enzyme cross-links to the phosphate located 3' to the 8-oxoguanine residue	Homo sapiens	?	-	?
additional information	cross-linking of active center with a series of reactive oligonucleotide duplexes containing both a single 8-oxoguanine residue and an O-ethyl-substituted diphosphate internucleotide group results in identification of seven phosphate groups on both strands of the DNA duplex specifically interacting with nucleophilic amino acids of the enzyme. L56 of enzyme cross-links to the phosphate located 3' to the 8-oxoguanine residue	Escherichia coli	?	-	?

Subunits

Subunits	Comment	Organism
More	cross-linking of active center with a series of reactive oligonucleotide duplexes containing both a single 8-oxoguanine residue and an O-ethyl-substituted diphosphate internucleotide group results in identification of eight phosphate groups on both strands of the DNA duplex specifically interacting with nucleophilic amino acids of the enzyme. L249 of enzyme cross-links to the phosphate located 3' to the 8-oxoguanine residue	Homo sapiens
More	cross-linking of active center with a series of reactive oligonucleotide duplexes containing both a single 8-oxoguanine residue and an O-ethyl-substituted diphosphate internucleotide group results in identification of seven phosphate groups on both strands of the DNA duplex specifically interacting with nucleophilic amino acids of the enzyme. L56 of enzyme cross-links to the phosphate located 3' to the 8-oxoguanine residue	Escherichia coli

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Release 2023.1 (January 2023)