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Literature summary for 3.2.2.23 extracted from

  • Song, K.; Hornak, V.; de Los Santos, C.; Grollman, A.P.; Simmerling, C.
    Computational analysis of the mode of binding of 8-oxoguanine to formamidopyrimidine-DNA glycosylase (2006), Biochemistry, 45, 10886-10894.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
8-oxoguanine is bound via E77 in syn conformation. In mutant E77S, which reflects the sequence of the Escherichia coli enzyme, 8-oxoguanine is preferentially bound in the anti conformation Geobacillus stearothermophilus

Protein Variants

Protein Variants Comment Organism
E77S in wild-type, 8-oxoguanine is bound via E77 in syn conformation. In mutant E77S, which reflects the sequence of the Escherichia coli enzyme, 8-oxoguanine is preferentially bound in the anti conformation Geobacillus stearothermophilus

Organism

Organism UniProt Comment Textmining
Geobacillus stearothermophilus P84131
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