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Literature summary for 3.2.1.62 extracted from
- Epigallocatechin-3-gallate inhibits lactase but is alleviated by salivary proline-rich proteins (2011), J. Agric. Food Chem., 59, 2734-2738.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| epigallocatechin-3-gallate | inhibits in vitro hydrolysis of lactose by lactase phlorizin hydrolase | Rattus norvegicus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| intestine | intestinal brush border enzyme | Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| lactose + H2O | - |
Rattus norvegicus | D-glucose + D-galactose | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| lactase phlorizin hydrolase | - |
Rattus norvegicus |
| LPH | - |
Rattus norvegicus |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.074 | - |
in 1.5 mM sodium phosphate buffer (pH 6.8), at 37°C | Rattus norvegicus | epigallocatechin-3-gallate | |
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