Inhibitors | Comment | Organism | Structure |
---|---|---|---|
D-galactono-1,4-lactone | competitive inhibition of lactase activity, Ki: 0.35 mM | Rattus sp. | |
D-glucono-1,5-lactone | competitive inhibition of lactase activity, Ki: 0.027 mM | Rattus sp. | |
phlorizin | competitive inhibition of lactase activity, Ki: 0.047 mM | Rattus sp. | |
Tris(hydroxymethyl)aminomethane | competitive inhibition of lactase activity, Ki: 4.5 mM | Rattus sp. |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.4 | - |
phlorizin | - |
Rattus sp. | |
0.4 | - |
phloretin-beta-D-galactoside | - |
Rattus sp. | |
1.1 | - |
4-O-beta-D-glucopyranosyl-D-glucopyranoside | - |
Rattus sp. | |
4.1 | - |
4-nitrophenyl-beta-D-glucopyranoside | - |
Rattus sp. | |
13.1 | - |
2-nitrophenyl-beta-D-galactopyranoside | - |
Rattus sp. | |
22.3 | - |
4-nitrophenyl-beta-D-galactopyranoside | - |
Rattus sp. | |
40 | - |
4-O-beta-D-galactopyranosyl-D-glucopyranoside | - |
Rattus sp. |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
brush border | - |
Rattus sp. | 5903 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O | Rattus sp. | best substrate | D-galactose + beta-D-glucose | - |
? | |
4-O-beta-D-glucopyranosyl-D-glucose + H2O | Rattus sp. | cellobiose | beta-D-glucose + D-glucose | - |
? | |
phlorizin + H2O | Rattus sp. | - |
phloretin + beta-D-glucose | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus sp. | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Rattus sp. |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
intestine | - |
Rattus sp. | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-nitrophenyl beta-D-galactopyranoside + H2O | - |
Rattus sp. | 2-nitrophenol + beta-D-galactose | - |
? | |
4-nitrophenyl beta-D-galactopyranoside + H2O | - |
Rattus sp. | 4-nitrophenol + beta-D-galactose | - |
? | |
4-nitrophenyl beta-D-glucopyranoside + H2O | - |
Rattus sp. | 4-nitrophenol + beta-D-glucose | - |
? | |
4-O-beta-D-galactopyranosyl-D-glucopyranoside + H2O | best substrate | Rattus sp. | D-galactose + beta-D-glucose | - |
? | |
4-O-beta-D-glucopyranosyl-D-glucose + H2O | cellobiose | Rattus sp. | beta-D-glucose + D-glucose | - |
? | |
phloretin-beta-D-galactoside + H2O | very low activity | Rattus sp. | phloretin + beta-D-galactose | - |
? | |
phlorizin + H2O | - |
Rattus sp. | phloretin + beta-D-glucose | - |
? |