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Literature summary for 3.2.1.45 extracted from

  • Ghisaidoobe, A.T.; van den Berg, R.J.; Butt, S.S.; Strijland, A.; Donker-Koopman, W.E.; Scheij, S.; van den Nieuwendijk, A.M.; Koomen, G.J.; van Loevezijn, A.; Leemhuis, M.; Wennekes, T.; van der Stelt, M.; van der Marel, G.A.; van Boeckel, C.A.; Aerts, J.M.; Overkleeft, H.S.
    Identification and development of biphenyl substituted iminosugars as improved dual glucosylceramide synthase/neutral glucosylceramidase inhibitors (2014), J. Med. Chem., 57, 9096-9104.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
(2R,3R,4R,5S)-1-(5-[[3',5'-bis(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-1-(5-[[4-(1,3-benzodioxol-5-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-1-(5-[[4-(2,3-dihydro-1,4-benzodioxin-6-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-1-(5-[[4-(2-fluoropyridin-4-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-1-(5-[[4-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-1-(5-[[4-(6-fluoropyridin-3-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-1-[5-(benzyloxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-1-[5-(biphenyl-2-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-1-[5-(biphenyl-3-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)-2,2-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)-4,4-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-1-[5-(cyclohexylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-1-[5-(hexyloxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-1-[5-[(1R)-1-(biphenyl-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-1-[5-[(1S)-1-(biphenyl-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-1-[5-[(2'-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-1-[5-[(2-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-1-[5-[(3'-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-1-[5-[(3-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-1-[5-[(3beta,17alpha,20S)-cholestan-3-yloxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-1-[5-[(4'-chlorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-1-[5-[(4'-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]oxy]pentyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[2-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[3-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4'-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(pyridin-3-yl)benzyl]oxy]pentyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(pyridin-4-yl)benzyl]oxy]pentyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(pyrimidin-5-yl)benzyl]oxy]pentyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(4,6,8a,10c-tetrahydropyren-1-ylmethoxy)pentyl]piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(naphthalen-2-ylmethoxy)pentyl]piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(phenanthren-9-ylmethoxy)pentyl]piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(2'-methoxybiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(2'-methylbiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(3'-methoxybiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(3'-methylbiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(4'-methoxybiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(4'-methylbiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(5-phenylpyridin-2-yl)methoxy]pentyl]piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(5R)-octahydro-1H-2,5-methanoinden-6-ylmethoxy]pentyl]piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-[6-[(3R)-tricyclo[3.3.1.13,7]dec-1-ylmethoxy]hexyl]piperidine-3,4,5-triol
-
Homo sapiens
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-[6-[(3R)-tricyclo[3.3.1.13,7]dec-1-yl]hexyl]piperidine-3,4,5-triol
-
Homo sapiens
(2R,3S,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3S,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2R,3S,4R,5S)-2-(hydroxymethyl)-1-[5-[(3R)-tricyclo[3.3.1.13,7]dec-1-ylmethoxy]pentyl]piperidine-3,4,5-triol
-
Homo sapiens
(2S,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2S,3R,4R,5S)-1-[5-(8a,10c-dihydropyren-1-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2S,3R,4R,5S)-1-[5-(benzyloxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2S,3R,4R,5S)-1-[5-(biphenyl-2-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2S,3R,4R,5S)-1-[5-(biphenyl-3-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2S,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)-2,2-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2S,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)-4,4-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2S,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2S,3R,4R,5S)-1-[5-(cyclohexylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2S,3R,4R,5S)-1-[5-(hexyloxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2S,3R,4R,5S)-1-[5-[(1R)-1-(biphenyl-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2S,3R,4R,5S)-1-[5-[(1S)-1-(biphenyl-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2S,3R,4R,5S)-1-[5-[(2-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2S,3R,4R,5S)-1-[5-[(3-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2S,3R,4R,5S)-1-[5-[(3beta,17alpha,20S)-cholest-5-en-3-yloxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
-
Homo sapiens
(2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]oxy]pentyl)piperidine-3,4,5-triol
-
Homo sapiens
(2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[2-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
-
Homo sapiens
(2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[3-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
-
Homo sapiens
(2S,3R,4R,5S)-2-(hydroxymethyl)-1-[(5Z)-6-[(3R)-tricyclo[3.3.1.13,7]dec-1-yl]hex-5-en-1-yl]piperidine-3,4,5-triol
-
Homo sapiens
(2S,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(naphthalen-2-ylmethoxy)pentyl]piperidine-3,4,5-triol
-
Homo sapiens
(2S,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(phenanthren-9-ylmethoxy)pentyl]piperidine-3,4,5-triol
-
Homo sapiens
(2S,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(1R,5S)-tricyclo[3.3.1.13,7]dec-2-ylmethoxy]pentyl]piperidine-3,4,5-triol
-
Homo sapiens
(2S,3R,4R,5S)-2-(hydroxymethyl)-1-[6-[(3R)-tricyclo[3.3.1.13,7]dec-1-ylmethoxy]hexyl]piperidine-3,4,5-triol
-
Homo sapiens
(2S,3R,4R,5S)-2-(hydroxymethyl)-1-[6-[(3S)-tricyclo[3.3.1.13,7]dec-1-yl]hexyl]piperidine-3,4,5-triol
-
Homo sapiens
4'-[([5-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]pentyl]oxy)methyl]biphenyl-2-carbonitrile
-
Homo sapiens
4'-[([5-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]pentyl]oxy)methyl]biphenyl-3-carbonitrile
-
Homo sapiens
4'-[([5-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]pentyl]oxy)methyl]biphenyl-4-carbonitrile
-
Homo sapiens
miglitol
-
Homo sapiens
miglustat
-
Homo sapiens
N-[(3R)-tricyclo[3.3.1.13,7]dec-1-yl]-6-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]hexanamide
-
Homo sapiens
N-[(3R)-tricyclo[3.3.1.13,7]dec-1-yl]-6-[(2S,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]hexanamide
-
Homo sapiens
N-[5-(adamantan-1-yl-methoxy)pentyl]-L-ido-1-deoxynojirimycin
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P04062
-
-
Homo sapiens Q9HCG7
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glucosylceramide + H2O
-
Homo sapiens beta-D-glucose + ceramide
-
?

Synonyms

Synonyms Comment Organism
acid glucosylceramidase
-
Homo sapiens
GBA1
-
Homo sapiens
GBA2
-
Homo sapiens
neutral glucosylceramidase
-
Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00000008
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(3-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.00000008
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(2-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.00000008
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[2-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
0.0000001
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[3-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
0.0000001
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[2-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
0.00000012
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[3-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
0.0000004
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(3-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.0000005
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(2'-methylbiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
0.0000006
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(2-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000001
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens N-[5-(adamantan-1-yl-methoxy)pentyl]-L-ido-1-deoxynojirimycin
0.000001
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(5R)-octahydro-1H-2,5-methanoinden-6-ylmethoxy]pentyl]piperidine-3,4,5-triol
0.000001
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(benzyloxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000001
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(naphthalen-2-ylmethoxy)pentyl]piperidine-3,4,5-triol
0.000001
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(naphthalen-2-ylmethoxy)pentyl]piperidine-3,4,5-triol
0.000001
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(8a,10c-dihydropyren-1-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000001
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(4'-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000001
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(3'-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000001
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)-4,4-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000001
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(1R)-1-(biphenyl-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000001
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3S,4R,5S)-2-(hydroxymethyl)-1-[5-[(3R)-tricyclo[3.3.1.13,7]dec-1-ylmethoxy]pentyl]piperidine-3,4,5-triol
0.000002
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens N-[5-(adamantan-1-yl-methoxy)pentyl]-L-ido-1-deoxynojirimycin
0.000002
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[6-[(3R)-tricyclo[3.3.1.13,7]dec-1-ylmethoxy]hexyl]piperidine-3,4,5-triol
0.000002
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000002
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(1R,5S)-tricyclo[3.3.1.13,7]dec-2-ylmethoxy]pentyl]piperidine-3,4,5-triol
0.000002
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(3'-methylbiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
0.000002
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens 4'-[([5-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]pentyl]oxy)methyl]biphenyl-3-carbonitrile
0.000002
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(2'-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000002
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(4'-chlorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000002
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[4-(1,3-benzodioxol-5-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000002
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(biphenyl-3-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000002
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(1S)-1-(biphenyl-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000002
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(biphenyl-3-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000002
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)-2,2-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000002
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)-4,4-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000002
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3S,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.0000025
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[6-[(3R)-tricyclo[3.3.1.13,7]dec-1-ylmethoxy]hexyl]piperidine-3,4,5-triol
0.000003
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(4,6,8a,10c-tetrahydropyren-1-ylmethoxy)pentyl]piperidine-3,4,5-triol
0.000003
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(benzyloxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000003
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000003
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(4'-methylbiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
0.000003
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(2'-methoxybiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
0.000003
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens 4'-[([5-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]pentyl]oxy)methyl]biphenyl-4-carbonitrile
0.000003
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(biphenyl-2-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000003
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(5-phenylpyridin-2-yl)methoxy]pentyl]piperidine-3,4,5-triol
0.000003
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(1S)-1-(biphenyl-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000003
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(1R)-1-(biphenyl-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000003
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(biphenyl-2-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000004
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(cyclohexylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000004
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[4-(2-fluoropyridin-4-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000005
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(3beta,17alpha,20S)-cholest-5-en-3-yloxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000005
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(3beta,17alpha,20S)-cholestan-3-yloxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000005
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens 4'-[([5-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]pentyl]oxy)methyl]biphenyl-2-carbonitrile
0.000005
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[4-(6-fluoropyridin-3-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000006
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(cyclohexylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000008
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[(5Z)-6-[(3R)-tricyclo[3.3.1.13,7]dec-1-yl]hex-5-en-1-yl]piperidine-3,4,5-triol
0.000009
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens N-[(3R)-tricyclo[3.3.1.13,7]dec-1-yl]-6-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]hexanamide
0.00001
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[6-[(3R)-tricyclo[3.3.1.13,7]dec-1-yl]hexyl]piperidine-3,4,5-triol
0.00001
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(4'-methoxybiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
0.00001
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4'-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
0.00001
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(pyridin-4-yl)benzyl]oxy]pentyl)piperidine-3,4,5-triol
0.00001
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(pyridin-3-yl)benzyl]oxy]pentyl)piperidine-3,4,5-triol
0.00001
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)-2,2-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000015
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens N-[(3R)-tricyclo[3.3.1.13,7]dec-1-yl]-6-[(2S,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]hexanamide
0.000015
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[3',5'-bis(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
0.000015
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[4-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
0.00002
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(3beta,17alpha,20S)-cholest-5-en-3-yloxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.00002
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[6-[(3S)-tricyclo[3.3.1.13,7]dec-1-yl]hexyl]piperidine-3,4,5-triol
0.00002
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(3'-methoxybiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
0.000025
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(pyrimidin-5-yl)benzyl]oxy]pentyl)piperidine-3,4,5-triol
0.00003
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[4-(2,3-dihydro-1,4-benzodioxin-6-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
0.00006
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[6-[(3R)-tricyclo[3.3.1.13,7]dec-1-yl]hexyl]piperidine-3,4,5-triol
0.00007
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(2'-methylbiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
0.0001
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens N-[5-(adamantan-1-yl-methoxy)pentyl]-L-ido-1-deoxynojirimycin
0.0001
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[6-[(3R)-tricyclo[3.3.1.13,7]dec-1-ylmethoxy]hexyl]piperidine-3,4,5-triol
0.0001
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[2-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
0.0001
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]oxy]pentyl)piperidine-3,4,5-triol
0.0001
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(phenanthren-9-ylmethoxy)pentyl]piperidine-3,4,5-triol
0.0001
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]oxy]pentyl)piperidine-3,4,5-triol
0.000125
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)-2,2-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.0002
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(2-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.0002
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[3-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
0.0002
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3S,4R,5S)-2-(hydroxymethyl)-1-[5-[(3R)-tricyclo[3.3.1.13,7]dec-1-ylmethoxy]pentyl]piperidine-3,4,5-triol
0.0002
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(phenanthren-9-ylmethoxy)pentyl]piperidine-3,4,5-triol
0.00025
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(4'-methylbiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
0.00025
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(3'-methylbiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
0.00025
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(3'-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.00025
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[4-(2,3-dihydro-1,4-benzodioxin-6-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
0.00025
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(3-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.00025
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol
0.0003
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(benzyloxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.0003
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(biphenyl-3-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.0003
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)-4,4-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.0003
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(1R)-1-(biphenyl-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.0003
-
isoform GBA2, pH and temperature not specified in the publication Homo sapiens (2R,3S,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol
0.00035
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens 4'-[([5-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]pentyl]oxy)methyl]biphenyl-4-carbonitrile
0.0004
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(5R)-octahydro-1H-2,5-methanoinden-6-ylmethoxy]pentyl]piperidine-3,4,5-triol
0.0004
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.0004
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(4'-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.0005
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens N-[(3R)-tricyclo[3.3.1.13,7]dec-1-yl]-6-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]hexanamide
0.0005
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(3beta,17alpha,20S)-cholest-5-en-3-yloxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.0005
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(3beta,17alpha,20S)-cholestan-3-yloxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.0005
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(4,6,8a,10c-tetrahydropyren-1-ylmethoxy)pentyl]piperidine-3,4,5-triol
0.0005
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(4'-chlorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.0005
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[4-(1,3-benzodioxol-5-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
0.0006
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(2'-methoxybiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
0.0006
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens 4'-[([5-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]pentyl]oxy)methyl]biphenyl-2-carbonitrile
0.0006
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(2'-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.0007
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens 4'-[([5-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]pentyl]oxy)methyl]biphenyl-3-carbonitrile
0.0008
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4'-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
0.0008
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[3',5'-bis(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
0.001
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(naphthalen-2-ylmethoxy)pentyl]piperidine-3,4,5-triol
0.00125
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(biphenyl-2-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.0015
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-(cyclohexylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.0015
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(5-phenylpyridin-2-yl)methoxy]pentyl]piperidine-3,4,5-triol
0.002
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens N-[5-(adamantan-1-yl-methoxy)pentyl]-L-ido-1-deoxynojirimycin
0.002
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(pyridin-4-yl)benzyl]oxy]pentyl)piperidine-3,4,5-triol
0.002
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[4-(2-fluoropyridin-4-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
0.0025
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]oxy]pentyl)piperidine-3,4,5-triol
0.0025
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(4'-methoxybiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
0.0025
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(3'-methoxybiphenyl-4-yl)methoxy]pentyl]piperidine-3,4,5-triol
0.003
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[4-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
0.003
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(pyridin-3-yl)benzyl]oxy]pentyl)piperidine-3,4,5-triol
0.003
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-(5-[[4-(6-fluoropyridin-3-yl)benzyl]oxy]pentyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
0.005
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[6-[(3R)-tricyclo[3.3.1.13,7]dec-1-ylmethoxy]hexyl]piperidine-3,4,5-triol
0.005
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[3-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
0.006
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[2-(trifluoromethyl)biphenyl-4-yl]methoxy]pentyl)piperidine-3,4,5-triol
0.006
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(2-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.008
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(3-fluorobiphenyl-4-yl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.01
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(phenanthren-9-ylmethoxy)pentyl]piperidine-3,4,5-triol
0.01
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[5-[(1R,5S)-tricyclo[3.3.1.13,7]dec-2-ylmethoxy]pentyl]piperidine-3,4,5-triol
0.01
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(benzyloxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.01
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[4-(pyrimidin-5-yl)benzyl]oxy]pentyl)piperidine-3,4,5-triol
0.01
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(1S)-1-(biphenyl-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.01
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(1R)-1-(biphenyl-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.012
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[(5Z)-6-[(3R)-tricyclo[3.3.1.13,7]dec-1-yl]hex-5-en-1-yl]piperidine-3,4,5-triol
0.0125
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)-4,4-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.015
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-[(3beta,17alpha,20S)-cholest-5-en-3-yloxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.015
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(8a,10c-dihydropyren-1-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.015
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(biphenyl-2-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.02
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.02
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(biphenyl-3-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.025
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[6-[(3S)-tricyclo[3.3.1.13,7]dec-1-yl]hexyl]piperidine-3,4,5-triol
0.04
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens N-[(3R)-tricyclo[3.3.1.13,7]dec-1-yl]-6-[(2S,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]hexanamide
0.05
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-(5-[[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]oxy]pentyl)piperidine-3,4,5-triol
0.05
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(naphthalen-2-ylmethoxy)pentyl]piperidine-3,4,5-triol
0.06
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(cyclohexylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.2
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3S,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.32
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3S,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol
0.4
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2R,3R,4R,5S)-1-[5-[(1S)-1-(biphenyl-4-yl)ethoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.5
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-1-[5-(biphenyl-4-ylmethoxy)-2,2-difluoropentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol
0.6
-
isoform GBA1, pH and temperature not specified in the publication Homo sapiens (2S,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(phenanthren-9-ylmethoxy)pentyl]piperidine-3,4,5-triol