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Literature summary for 3.2.1.45 extracted from

  • Boot, R.G.; Verhoek, M.; Donker-Koopman, W.; Strijland, A.; van Marle, J.; Overkleeft, H.S.; Wennekes, T.; Aerts, J.M.
    Identification of the non-lysosomal glucosylceramidase as beta-glucosidase 2 (2007), J. Biol. Chem., 282, 1305-1312.
    View publication on PubMed
Search for more literature for 3.2.1.45

Cloned(Commentary)

Cloned (Comment) Organism
expressed in COS-7 cells Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
additional information not inhibited by conduritol B epoxide Homo sapiens
N-(5-adamantane-1-yl-methoxy)pentyl-deoxynojirimycin extremely potent inhibitor for GBA2 Homo sapiens
N-butyldeoxynojirimycin extremely potent inhibitor for GBA2 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cell surface
-
 Homo sapiens 9986
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
spleen
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-methylumbelliferyl-beta-D-glucopyranoside + H2O
-
 Homo sapiens methylumbelliferone + beta-D-glucose
-
 ?
C6-NBD-glucosylceramide + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
beta-glucosidase 2
-
 Homo sapiens
bile acid beta-glucosidase
-
 Homo sapiens
GBA2
-
 Homo sapiens
NLGase
-
 Homo sapiens
non-lysosomal glucosylceramidase
-
 Homo sapiens