Protein Variants | Comment | Organism |
---|---|---|
N370S | Gaucher disease-causing mutation | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,4-dideoxy-1,4-imino-D-arabinitol | - |
Homo sapiens | |
1,5-dideoxy-1,5-iminoxylitol | potent inhibitor | Homo sapiens | |
1-deoxynojirimycin | - |
Homo sapiens | |
2R,5R-dihydroxymethyl-3R,4R-dihydroxypyrrolidine | - |
Homo sapiens | |
calystegine A3 | potent inhibitor | Homo sapiens | |
calystegine A5 | - |
Homo sapiens | |
calystegine B1 | potent inhibitor | Homo sapiens | |
calystegine B2 | potent inhibitor | Homo sapiens | |
calystegine B3 | - |
Homo sapiens | |
calystegine B4 | - |
Homo sapiens | |
calystegine C1 | potent inhibitor | Homo sapiens | |
castanospermine | - |
Homo sapiens | |
isofagomine | potent inhibitor | Homo sapiens | |
N-butyl-1-deoxynojirimycin | - |
Homo sapiens | |
N-butylisofagomine | - |
Homo sapiens | |
N-dodecyl-1-deoxynojirimycin | potent inhibitor | Homo sapiens | |
N-methylcalystegine B2 | - |
Homo sapiens | |
nojirimycin bisulfite | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | - |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
fibroblast | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-methylumbelliferyl-beta-D-glucopyranoside + H2O | - |
Homo sapiens | methylumbelliferone + beta-D-glucose | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Ceredase | - |
Homo sapiens |
Gcase | - |
Homo sapiens |
glucocerebrosidase | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00004 | - |
in 0.1 M citrate buffer (pH 5.2), using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate | Homo sapiens | isofagomine | |
0.00005 | - |
in 0.1 M citrate buffer (pH 5.2), using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate | Homo sapiens | N-dodecyl-1-deoxynojirimycin | |
0.001 | - |
in 0.1 M citrate buffer (pH 5.2), using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate | Homo sapiens | calystegine B2 | |
0.0023 | - |
in 0.1 M citrate buffer (pH 5.2), using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate | Homo sapiens | 1,5-dideoxy-1,5-iminoxylitol | |
0.0025 | - |
in 0.1 M citrate buffer (pH 5.2), using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate | Homo sapiens | calystegine B1 | |
0.0025 | - |
in 0.1 M citrate buffer (pH 5.2), using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate | Homo sapiens | calystegine C1 | |
0.0031 | - |
in 0.1 M citrate buffer (pH 5.2), using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate | Homo sapiens | calystegine A3 | |
0.019 | - |
in 0.1 M citrate buffer (pH 5.2), using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate | Homo sapiens | castanospermine | |
0.028 | - |
in 0.1 M citrate buffer (pH 5.2), using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate | Homo sapiens | nojirimycin bisulfite | |
0.031 | - |
in 0.1 M citrate buffer (pH 5.2), using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate | Homo sapiens | calystegine A5 | |
0.044 | - |
in 0.1 M citrate buffer (pH 5.2), using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate | Homo sapiens | N-butyl-isofagomine | |
0.076 | - |
in 0.1 M citrate buffer (pH 5.2), using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate | Homo sapiens | calystegine B3 | |
0.082 | - |
in 0.1 M citrate buffer (pH 5.2), using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate | Homo sapiens | calystegine B4 | |
0.16 | - |
in 0.1 M citrate buffer (pH 5.2), using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate | Homo sapiens | 1,4-dideoxy-1,4-imino-D-arabinitol | |
0.24 | - |
in 0.1 M citrate buffer (pH 5.2), using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate | Homo sapiens | 1-deoxynojirimycin | |
0.27 | - |
in 0.1 M citrate buffer (pH 5.2), using 4-methylumbelliferyl-beta-glucopyranoside as substrate | Homo sapiens | N-butyl-1-deoxynojirimycin | |
0.28 | - |
in 0.1 M citrate buffer (pH 5.2), using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate | Homo sapiens | 2R,5R-dihydroxymethyl-3R,4R-dihydroxypyrrolidine | |
0.32 | - |
in 0.1 M citrate buffer (pH 5.2), using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate | Homo sapiens | N-methyl-calystegine B2 |