Literature summary for 3.2.1.45 extracted from

Ikeda, K.; Kato, A.; Adachi, I.; Haraguchi, M.; Asano, N.
Alkaloids from the poisonous plant Ipomoea carnea: effects on intracellular lysosomal glycosidase activities in human lymphoblast cultures (2003), J. Agric. Food Chem., 51, 7642-7646.

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Inhibitors

Inhibitors	Comment	Organism	Structure
calystegine B1	-	Homo sapiens
calystegine B1	-	Rattus norvegicus
calystegine B2	-	Homo sapiens
calystegine B2	-	Rattus norvegicus
calystegine C1	-	Homo sapiens
calystegine C1	-	Rattus norvegicus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
lysosome	-	Homo sapiens	5764	-
lysosome	-	Rattus norvegicus	5764	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-
Rattus norvegicus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4-methylumbelliferyl glucoside + H2O	-	Homo sapiens	4-methylumbelliferone + D-glucose	-	?

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.0005	-	calystegine B1	pH 4.5, 37°C	Homo sapiens
0.0009	-	calystegine C1	pH 4.5, 37°C	Homo sapiens
0.0015	-	calystegine B1	pH 4.5, 37°C	Homo sapiens

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Release 2023.1 (January 2023)