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Literature summary for 3.2.1.23 extracted from

  • Balestrin, R.C.; Baldo, G.; Vieira, M.B.; Sano, R.; Coelho, J.C.; Giugliani, R.; Matte, U.
    Transient high-level expression of beta-galactosidase after transfection of fibroblasts from GM1 gangliosidosis patients with plasmid DNA (2008), Braz. J. Med. Biol. Res., 41, 283-288.
    View publication on PubMed

Application

Application Comment Organism
medicine transfection of beta-galactosidase gene to fibroblast cells in culture using liposomes. 24 h after transfection, treated cells show a higher specific enzyme activity than untreated cells. Cells maintained in culture for 7 days show values similar to those of untreated patients with GM1 gangliosidosis Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
transfection of fibroblast Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information transfection of beta-galactosidase gene to fibroblast cells in culture using liposomes. 24 h after transfection, treated cells show a higher specific enzyme activity than untreated cells. Cells maintained in culture for 7 days show values similar to those of untreated patients with GM1 gangliosidosis Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
patients with GM1 gangliosidosis
-

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast
-
Homo sapiens
-