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Literature summary for 3.2.1.21 extracted from
- Synthesis of multibranched australine derivatives from reducing castanospermine analogues through the amadori rearrangement of gem-diamine intermediates: selective inhibitors of beta-glucosidase (2014), J. Org. Chem., 79, 11722-11728.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 3,8-dibutylamino-7,8-dideoxy-5-octylimino-6-oxa-3-epi-australine | - |
Bos taurus |  |
| 3,8-dibutylamino-7,8-dideoxy-5-octylimino-6-oxa-3-epi-australine | - |
Prunus dulcis | |
| 7,8-dideoxy-3,8-didodecylamino-5-octylimino-6-oxa-3-epi-australine | - |
Bos taurus | |
| 7,8-dideoxy-3,8-didodecylamino-5-octylimino-6-oxa-3-epi-australine | - |
Prunus dulcis | |
| 7,8-dideoxy-3,8-dioctylamino-5-octylimino-6-oxa-3-epi-australine | - |
Bos taurus | |
| 7,8-dideoxy-3,8-dioctylamino-5-octylimino-6-oxa-3-epi-australine | - |
Prunus dulcis | |
| 7,8-dideoxy-3-hydroxy-8-octylamino-5-octylimino-6-oxa-3-epi-australine | - |
Bos taurus | |
| 7,8-dideoxy-3-hydroxy-8-octylamino-5-octylimino-6-oxa-3-epi-australine | - |
Prunus dulcis | |
| 7,8-dideoxy-8-dodecylamino-3-hydroxy-5-octylimino-6-oxa-3-epi-australine | - |
Bos taurus | |
| 7,8-dideoxy-8-dodecylamino-3-hydroxy-5-octylimino-6-oxa-3-epi-australine | - |
Prunus dulcis | |
| 8-butylamino-7,8-dideoxy-3-hydroxy-5-octylimino-6-oxa-3-epi-australine | - |
Bos taurus | |
| 8-butylamino-7,8-dideoxy-3-hydroxy-5-octylimino-6-oxa-3-epi-australine | - |
Prunus dulcis | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Prunus dulcis | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| beta-Glcase | - |
Bos taurus |
| beta-Glcase | - |
Prunus dulcis |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0029 | - |
7,8-dideoxy-8-dodecylamino-3-hydroxy-5-octylimino-6-oxa-3-epi-australine | pH and temperature not specified in the publication | Bos taurus | |
| 0.0096 | - |
7,8-dideoxy-3-hydroxy-8-octylamino-5-octylimino-6-oxa-3-epi-australine | pH and temperature not specified in the publication | Bos taurus | |
| 0.012 | - |
7,8-dideoxy-3,8-dioctylamino-5-octylimino-6-oxa-3-epi-australine | pH and temperature not specified in the publication | Bos taurus | |
| 0.025 | - |
7,8-dideoxy-3,8-didodecylamino-5-octylimino-6-oxa-3-epi-australine | pH and temperature not specified in the publication | Bos taurus | |
| 0.051 | - |
8-butylamino-7,8-dideoxy-3-hydroxy-5-octylimino-6-oxa-3-epi-australine | pH and temperature not specified in the publication | Bos taurus | |
| 0.056 | - |
7,8-dideoxy-8-dodecylamino-3-hydroxy-5-octylimino-6-oxa-3-epi-australine | pH and temperature not specified in the publication | Prunus dulcis | |
| 0.058 | - |
3,8-dibutylamino-7,8-dideoxy-5-octylimino-6-oxa-3-epi-australine | pH and temperature not specified in the publication | Bos taurus | |
| 0.223 | - |
3,8-dibutylamino-7,8-dideoxy-5-octylimino-6-oxa-3-epi-australine | pH and temperature not specified in the publication | Prunus dulcis | |
| 0.32 | - |
8-butylamino-7,8-dideoxy-3-hydroxy-5-octylimino-6-oxa-3-epi-australine | pH and temperature not specified in the publication | Prunus dulcis | |
| 0.367 | - |
7,8-dideoxy-3,8-didodecylamino-5-octylimino-6-oxa-3-epi-australine | pH and temperature not specified in the publication | Prunus dulcis | |
| 0.441 | - |
7,8-dideoxy-3,8-dioctylamino-5-octylimino-6-oxa-3-epi-australine | pH and temperature not specified in the publication | Prunus dulcis | |
| 0.484 | - |
7,8-dideoxy-3-hydroxy-8-octylamino-5-octylimino-6-oxa-3-epi-australine | pH and temperature not specified in the publication | Prunus dulcis | |
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