Cloned (Comment) | Organism |
---|---|
expressed in SK-N-BE neuroblastoma cells | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrial membrane | outer mitochondrial membrane | Homo sapiens | 31966 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Synonyms | Comment | Organism |
---|---|---|
NEU4L | - |
Homo sapiens |
sialidase | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
metabolism | NEU4 long is a downstream component of the PI3K/Akt signaling pathway required for retinoic acid-induced differentiation of neuroblastoma SK-N-BE cells | Homo sapiens |
physiological function | the proline-rich region of NEU4 long can enhance cell proliferation and retinoic acid-induced neuronal differentiation and it is also involved in NEU4 interaction with Akt, as well as in substrate recognition, modifying directly or through the interaction with other protein(s) the enzyme specificity toward sialylated glycoprotein(s) | Homo sapiens |