Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | construction of octyl galactosides and octyl N-acetyl-lactosamines as trans-sialidase inhibitors, inhibitor screening of the beta-thiogalactopyranoside library, overview | Trypanosoma cruzi |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma cruzi | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme catalyses the alpha-(2,3)-sialylation of non-reducing terminal beta-galactose residues, it is largely intolerant of substitution of the galactose 2 and 4 positions whereas substitution of the galactose 6 position is well tolerated, even the addition of a bulky sugar residue, glucose or galactose, does not impact negatively on TcTS binding and turnover, which highlights the potential of internal 6-substituted galactose residues to serve as enzyme acceptor substrates, substrate binding mode and site, overview | Trypanosoma cruzi | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
trans-sialidase | - |
Trypanosoma cruzi |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Trypanosoma cruzi |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
assay at | Trypanosoma cruzi |