Crystallization (Comment) | Organism |
---|---|
molecular dynamics simulation study of inhibitors oseltamivir, zanamivir and peramivir embedded in the catalytic site. In comparison with oseltamivir and zanamivir, peramivir shows strong direct ligand-enzyme hydrogen bonding, less space available in the N1 pocket, and it interacts tightly, via its OH group, with the D51 residue located in the 150-loop region | unidentified influenza virus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
oseltamivir | molecular dynamics simulation study. In comparison with oseltamivir and zanamivir, peramivir shows strong direct ligand-enzyme hydrogen bonding, less space available in the N1 pocket, and it interacts tightly, via its OH group, with the D51 residue located in the 150-loop region | unidentified influenza virus | |
peramivir | molecular dynamics simulation study | unidentified influenza virus | |
zanamivir | molecular dynamics simulation study | unidentified influenza virus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
unidentified influenza virus | - |
H5N1 avian influenza virus | - |