Literature summary for 3.2.1.18 extracted from

Yano, T.; Nobusawa, E.; Nagy, A.; Nakajima, S.; Nakajima, K.
Effects of single-point amino acid substitutions on the structure and function neuraminidase proteins in influenza A virus (2008), Microbiol. Immunol., 52, 216-223.

Search for more literature for 3.2.1.18

Protein Variants

Protein Variants	Comment	Organism
additional information	study on the effects of single-point amino acid substitutions on the structure and function of neuraminidase proteins. The rate of tolerant random one amino acid substitutions is 47%. Rates of tolerant substitutions for the stalk and for the surface and inner portion are 79%, 54%, and 19%, respectively. The ratio of mutations with which the enzyme loses neuraminidase activity, but is transported to the cell surface, decreases in proportion to the distance from the structural center of enzyme active site	influenza A virus

Organism

Organism	UniProt	Comment	Textmining
influenza A virus	-	type H2N2	-
influenza A virus A/tokyo/3/67	-	type H2N2	-

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)