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Literature summary for 3.2.1.18 extracted from

  • Shiozaki, K.; Yamaguchi, K.; Sato, I.; Miyagi, T.
    Plasma membrane-associated sialidase (NEU3) promotes formation of colonic aberrant crypt foci in azoxymethane-treated transgenic mice (2009), Cancer Sci., 100, 588-594.
    View publication on PubMed

Application

Application Comment Organism
medicine study on susceptibility of Neu3 transgenic mice to induction of colonic aberrant crypt foci by azoxymethane. Injection of with azoxymethane results in decreased GM3 and increased lactosylceramide content in transgenic colon mucosa. Up-regulation of Neu3 is important to the promotion stage of colorectal carcinogenesis Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
isoform Neu3
-

Source Tissue

Source Tissue Comment Organism Textmining