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Literature summary for 3.2.1.18 extracted from
- Characterization of a sialidase (neuraminidase) isolated from Clostridium chauvoei (Jakari strain) (2006), Cell Biochem. Funct., 24, 347-352.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 2,3 didehydroneuraminic acid | - |
Clostridium chauvoei |  |
| 2,3-didehydroneuraminic acid | competitive | Clostridium chauvoei | |
| diethyldicarbonate | - |
Clostridium chauvoei | |
| N-ethylmaleimide | - |
Clostridium chauvoei | |
| p-nitrophenyloxamic acid | competitive | Clostridium chauvoei | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.008 | - |
fetuin | - |
Clostridium chauvoei |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | activates | Clostridium chauvoei | |
| Mg2+ | activates | Clostridium chauvoei | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 65000 | - |
x * 65000, SDS-PAGE | Clostridium chauvoei |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Clostridium chauvoei | - |
Jakari strain | - |
| Clostridium chauvoei Jakari | - |
Jakari strain | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| fetuin + H2O | - |
Clostridium chauvoei | ? | - |
? | |
| fetuin + H2O | - |
Clostridium chauvoei Jakari | ? | - |
? | |
| additional information | the enzyme cleaves sialic acids from RBC ghosts of sheep, horse, goat, cattle, pig and mice as well as mouse brain cells | Clostridium chauvoei | ? | - |
? | |
| additional information | the enzyme cleaves sialic acids from RBC ghosts of sheep, horse, goat, cattle, pig and mice as well as mouse brain cells | Clostridium chauvoei Jakari | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 65000, SDS-PAGE | Clostridium chauvoei |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 40 | - |
- |
Clostridium chauvoei |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 4.5 | - |
- |
Clostridium chauvoei |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.03 | - |
p-nitrophenyl oxamic acid | - |
Clostridium chauvoei | |
| 0.04 | - |
2,3 didehydroneuraminic acid | - |
Clostridium chauvoei | |
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