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Literature summary for 3.2.1.18 extracted from
- Characterization of neuraminidase activity of cultured human fibroblasts (1979), Biochim. Biophys. Acta, 568, 39-48.
General Stability
| General Stability | Organism |
|---|---|
| labile towards freezing and thrawing | Homo sapiens |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.36 | - |
fetuin | - |
Homo sapiens | |
| 1.1 | - |
2-(3-methoxyphenyl)-N-acetylneuraminic acid | - |
Homo sapiens |  |
| 3 | - |
N-acetylneuraminyllactose | - |
Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| fibroblast | - |
Homo sapiens | - |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -70°C, after 48 h inactivated | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2-(3-methoxyphenyl)-N-acetylneuraminic acid + H2O | - |
Homo sapiens | 3-methoxyphenol + N-acetylneuraminic acid | - |
? | |
| fetuin + H2O | - |
Homo sapiens | ? | - |
? | |
| N-acetylneuraminyllactose + H2O | - |
Homo sapiens | N-acetylneuraminic acid + lactose | - |
? | |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 52 | - |
inactivated | Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 4.2 | 4.6 | - |
Homo sapiens |
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