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Literature summary for 3.2.1.17 extracted from

  • Evran, S.; Yasa, I.; Telefoncu, A.
    Modification of lysozyme with oleoyl chloride for broadening the antimicrobial specificity (2010), Prep. Biochem. Biotechnol., 40, 316-325.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information a oleyl group is covalently bound to free amino groups, N-terminal amino group and epsilon-amino groups of lysine residues, on lysozyme. No decrease in the activity of lysozyme derivatives occurs compared to native lysozyme, but the oleyl group, as a hydrophobic compound, facilitated the interaction of lysozyme with the bacterial membrane through hydrophobic interaction Gallus gallus

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
Gallus gallus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Gallus gallus antimicrobial activities of lysozyme derivatives are tested against Staphylococcus aureus ATCC 121002 and Escherichia coli ATCC 29998, as gram-positive and gram-negative representatives, respectively. The enzyme is activa against Staphylococcus aureus, but only poorly against Escherichia coli, overview ?
-
?

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
commercial preparation
-
Gallus gallus
-
egg white
-
Gallus gallus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information antimicrobial activities of lysozyme derivatives are tested against Staphylococcus aureus ATCC 121002 and Escherichia coli ATCC 29998, as gram-positive and gram-negative representatives, respectively. The enzyme is activa against Staphylococcus aureus, but only poorly against Escherichia coli, overview Gallus gallus ?
-
?
additional information a suspension of Micrococcus lysodeikticus is used as a substrate Gallus gallus ?
-
?

Synonyms

Synonyms Comment Organism
mucopeptide N-acetylmuramic acid hydrolase
-
Gallus gallus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Gallus gallus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
assay at Gallus gallus