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Literature summary for 3.2.1.17 extracted from

  • Wu, X.; Narsimhan, G.
    Effect of surface concentration on secondary and tertiary conformational changes of lysozyme adsorbed on silica nanoparticles (2008), Biochim. Biophys. Acta, 1784, 1694-1701.
    View publication on PubMed

Application

Application Comment Organism
analysis kinetics of tertiary conformation of lysozyme adsorbed on 90 nm silica nanoparticles. A rapid initial unfolding, followed by a much slower refolding and subsequent unfolding is observed, with the extent of unfolding being higher at lower surface concentration, higher ionic strengths, higher 2,2,2-trifluoroethanol and dithiothreitol concentrations and at pH 9. alpha-Helix content is lower for adsorbed lysozyme compared to bulk with a corresponding increase in beta-sheet and random coil Gallus gallus

Organism

Organism UniProt Comment Textmining
Gallus gallus P00698
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Renatured (Commentary)

Renatured (Comment) Organism
dithiothreitol decreases content of alpha-helices with a corresponding increase in random coil, while 2,2,2-trifluoroethanol has a negligible effect on secondary structure Gallus gallus

Source Tissue

Source Tissue Comment Organism Textmining
commercial preparation
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Gallus gallus
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